A total of fifty-three people have since been confirmed dead in Wednesday night’s road accident at Kintampo in the Brong Ahafo region.
More deaths have since been recorded at the hospital but the number is yet to be confirmed.
The accident happened around 8pm a few metres away from the Kintampo township on the way to Tamale and near the waterfalls.
It involved a Metro Mass Transit (MMT) bus which was heading towards Northern Ghana and a cargo truck loaded with tomatoes.
Many passengers were trapped under the bus. The injured were taken to hospital for medical attention.
The accident resulted in a heavy vehicular traffic In the area as vehicles queued, waiting for the accident scene to be cleared.
The police said their initial investigations indicated the MMT bus had brake problems.
The driver was said to have earlier detected the brake problem around Techiman, stopped to check on it but continued the journey until the brake completely failed a few meters after the Kintampo township.
He was said to have lost control over the vehicle whilst descending the steep in the Kintampo waterfalls area and crashed head on with a cargo truck loaded with tomatoes in a curve.